The evolution of resistance and counter-resistance in Drosophila and its natural enemies

The evolution of resistance and counter-resistance in Drosophila and its natural enemies

Braconid wasp Asobara tabida searching for Drosophila larvae in a patch of food medium

Our work on the interaction between Drosophila and its natural enemies, especially parastoids, was carried out at the Imperial College campus at Silwood Park between 1995 and 2006.  Throughout it was masterminded by Lex Kraaijeveld now a lecturer at the University of Southampton.

The PhD students who worked on the project were:
Mark Fellowes, now at the University of Reading
Darren Green, now at the University of Stirling
Amy Sanders, now at the Wellcome Trust
Pete Futerman
Roshan Vijendravarma, now at the University of Lausanne

Selected publications

  • Kraaijeveld, A.R., Emmett, D.A. & Godfray, H.C.J. 1997 Absence of direct sexual selection for parasitoid resistance in Drosophila melanogaster.  Journal of Evolutionary Biology 10, 337-342.
  • Kraaijeveld, A.R. & Godfray, H.C.J. 1997 Trade-off between parasitoid resistance and larval competitive ability in Drosophila melanogaster.  Nature 389, 278-280.
  • Kraaijeveld, A.R., van Alphen, J.J.M. & Godfray, H.C.J. 1998 Coevolution of host resistance and parasitoid virulence.  Parasitology 116, S29-S45.
  • Fellowes, M.D.E., Masnatta, P., Kraaijeveld, A.R. & Godfray, H.C.J. 1998 Pupal parasitoid attack influences the relative fitness of Drosophila that have encapsulated larval parasitoids.  Ecological Entomology 23, 281-284.
  • Fellowes, M.D.E., Kraaijeveld, A.R. & Godfray, H.C.J. 1998 Trade-off associated with selection for increased ability to resist parasitoid attack in Drosophila melanogaster.  Proceedings of the Royal Society, London 265, 1553-1558.
  • Sasaki, A. & Godfray, H.C.J. 1999  A model for the coevolution of resistance and virulence in coupled host-parasitoid interactions. Proceedings of the Royal Society, London B. 266, 455-463.
  • Fellowes, M.D.E., Kraaijeveld, A.R. & Godfray, H.C.J. 1999 The relative fitness of Drosophila melanogaster (Diptera, Drosophilidae) that have successfully defended themselves against the parasitoid Asobara tabida (Hymenoptera, Braconidae).  Journal of Evolutionary Biology 12, 123-128.
  • Kraaijeveld, A.R. & Godfray, H.C.J. 1999  Geographical patterns in the evolution of resistance and virulence in Drosophila and its parasitoids. American Naturalist 153, S61-S74 (http://ora.ouls.ox.ac.uk/objects/uuid:197b8412-29eb-4aa6-83b1-153f830f6148).
  • Fellowes, M.D.E., Kraaijeveld, A.R. & Godfray, H.C.J. 1999 Cross-resistance following artificial selection for increased defence against parasitoids in Drosophila melanogaster.  Evolution 53, 966-972.
  • Fellowes, M.D.E., Kraaijeveld, A.R. & Godfray, H.C.J. 1999 Association between feeding rate and parasitoid resistance in Drosophila melanogaster. Evolution 53, 1302-1305.
  • Fellowes, M.D.E. & Godfray, H.C.J. 2000 The evolutionary ecology of resistance to parasitoids by Dropsophila. Heredity 84, 1-8.
  • Green, D.M., Kraaijeveld, A.R. & Godfray, H.C.J. 2000 Evolutionary interactions between Drosophila melanogaster and its parasitoid Asobara tabida.  Heredity 85, 450-458.
  • Kraaijeveld, A.R. & Godfray, H.C.J. 2001 Is there local adaptation in Drosophila-parasitoid interactions?  Evolutionary Ecology Research 3, 107-118.
  • Kraaijeveld, A.R., Limentani, E.C. & Godfray, H.C.J. 2001 Basis of trade-off between parasitoid resistance and larval competitive ability in Drosophila melanogaster. Proceedings of the Royal Society, London B. 268, 259-261.
  • Tiën, N., Boyle, D., Kraaijeveld, A.R. & Godfray,H.C.J.  2001 Competitive ability of parasitised Drosophila larvae. Evolutionary Ecology Research 3, 747-757.
  • Kraaijeveld, A.R., Hutcheson, K.A., Limentani, E.C. & Godfray, H.C.J. 2001  Costs of counter-defences to host resistance in a parasitoid of Drosophila Evolution 55, 1815-1821.
  • Kraaijeveld, A.R., Ferrari, J. & Godfray, H.C.J. 2002 Costs of resistance in insect-parasite and insect-parasitoid interactions.  Parasitology 125, S71-S82 (http://ora.ouls.ox.ac.uk/objects/uuid:298045d5-a219-40aa-8303-f7d543a84b7e).
  • Kraaijeveld, A.R. & Godfray, H.C.J. 2003 Potential life history costs of parasitoid avoidance in Drosophila melanogaster.  Evolutionary Ecology Research 5, 1251-1261.
  • Godfray, H.C.J., Fellowes, M.D.E. & Kraaijeveld, A.R. 2005 Coevolution of resistance and virulence in host-parasitoid interactions.  In Entomology at the Land Grant University; Perspectives from the Texas A & M University Department Centenary (ed. Heinz, K.M., Frisbie, R.E. & Bográn, C.E.), pp. 142-164, Texas A & M University Press.
  • Sanders A.E., Scarborough C., Hopkins M., Layen S., Kraaijeveld A.R. & Godfray H.C.J. 2005  Evolutionary change in parasitoid resistance under crowded conditions in Drosophila melanogaster.  Evolution 59, 1292-1299.
  • Wertheim, B., Kraaijeveld, A.R., Schuster, E., Blanc, E., Hopkins, M., Pletcher, S.D., Strand, M.R., Partridge, L. & Godfray, H.C.J. 2005 Genome-wide gene expression in response to parasitoid attack in Drosophila.  Genome Biology 6:R94 (doi:10.1186/gb-2005-6-11-r94)
  • Futerman, P.H., Layen, S.J., Kotzen, M.L., Franzen, C, Kraaijeveld, A.R. and Godfray, H.C.J. 2006.  Fitness effects and transmission routes of a microsporidian parasite infecting Drosophila and its parasitoids.  Parasitology 132, 479-492 (http://ora.ouls.ox.ac.uk/objects/uuid:1d2467f5-a979-47c9-a58b-b30e8f5b84c1).
  • Kraaijeveld, A.R. & Godfray, H.C.J. 2008 Linking behavioural ecology to the study of host resistance and parasitoid counter-resistance.  In Behavioural Ecology of Insect Parasitoids pp. 315-334 (ed. Wajnberg, E., Bernstein, C. & van Alphen, J.J.M.), Blackwell, Oxford.
  • Kraaijeveld, A.R., Barker, C.L. & Godfray, H.C.J. 2008 Stage-specific sex differences in Drosophila immunity to parasites and pathogens.  Evolutionary Ecology 22, 217-228 (DOI: 10.1007/s10682-007-9171-y).
  • Kraaijeveld, A.R. & Godfray, H.C.J. 2008 Selection for resistance to a fungal pathogen in Drosophila melanogaster.  Heredity 100, 400-406.
  • Vijendravarma, R.K., Godfray, H.C.J., Kraaijeveld, A.R. 2008 Infection of Drosophila melanogaster by Tubulinosema kingi: stage-specific susceptibility, within-host proliferation and cellular immune response. Journal of Invertebrate Pathology 99, 239-241.DOI: 10.1016/j.jip.2008.02.014
  • Vijendravarma, R.K., Kraaijeveld, A.R. & Godfray, H.C.J.  2009 Experimental evolution shows Drosophila melanogaster resistance to a microsporidian pathogen has a fitness cost.  Evolution 63, 104-114.